Mike you are so right about DAVID. As the line moved forward, and I turned the corner and beheld that glorious statue, I was so overcome-it truly took my breath away!
I agree.
I studied art history in college (and probably saw photographs of David hundreds of times), and seeing the David statue for real still took my breath away.
Definitely get tickets in advance.
I didn't love the Uffizi, but there is a little restaurant across the Arno, I think called something like "The Laughing Boar" which was great. It's hard to beat the food in Florence. And have some gelato (you won't be sorry for having wasted the calories on it).
We also went to a little town in Tuscany called Rada, which was a really cute hilltop city (and had a fun, local wine enoteca), and drove to Sienna, which was beautiful. Sienna is also where we got cussed out by an older Italian guy for committing a parking faux pas (at least we think he was cussing us out, it was in Italian, and we didn't understand).
The driving maps are not great, even from the rental car companies, so caveat emptor. (we actually spent some time in a town in Tuscany, that we actually thought was another town, but it was still nice).
You will have a great trip! We loved Italy (and we only saw Venice and Florence).