Santiago de Chile was en route on our rtw-trips quite a few times. LAN Chile is also one of our favorite airlines.
Santiago itself is a big city, plenty to do and see for a few days. Palaces, plazas, museums, interesting neighborhoods. Take a funicular to the Parque Metropolitano hills, enjoy the view, Cerro San Cristobal, the zoo and walk back down. We didn't check the cultural offerings but I've heard they are pretty good, especially the jazz clubs.
The best thing about Santiago is that there's so much nearby. Towards the coastal Valparaiso, which itself is worth a visit, there are plenty of wine regions to visit. Nearby is also San Alfonso del Mar with the world's largest swimming pool (3324 ft long!). And on the other side there are the mountains for great skiing and mountain climbing. To the south you get even more wine regions and of course the lake district.
The food in Chile is superb. They have great beef, comparable to Argentina. The other ingredients are excellent quality, very fresh. And the wines..
We did a two+ day private wine tour with Michael Ayandokun of Winetours Valparaiso. He was born in Nigeria, lived in London, fell in love and moved to Valparaiso and does wine tours and ski trips among other things. Our tours were around the Casablanca valley known for it's whites, especially as we weren't very familiar with white wines. Some of the vineyards have good tourist facilities with tours and restaurants, sometimes we would sit with the owner by the vineyard, looking the grapes grow, drink their wines and eat local cheese. Just superb. We were staying at Manoir Atkinson in Valparaiso, great location.
The lake district, "Switzerland of South America", was just stunning. We started from Lake Villarrica next to the Villarrica volcano. The vista is just so beautiful there with the cristal clear lakes, blue sky, and the mountains. You can do a lot of things, sailing, kayaking, fishing, and you can ski on the (active) volcano during the winter. The area is known for it's hot springs and we can highly recommend Termas Geometricas. It's quite new and it's built to the nature, unlike the most famous ones that look like tiled swimming pools. We had our "christmas sauna" there, followed by a "christmas dinner" -- eating great beef and wine in Pucon. We stayed at Antumalal, classic architecture and beautiful views by the lake. We flew from Santiago to Temuco and rent a car there.
From Villarrica we drove to Huilo Huilo, which is by far one of the most interesting places we've ever been to. It's a huge biological reserve. The accommodation is in two buildings, Baobap which is built around a three and Montana Magica which is built like a green volcano with a waterfall on it. Everything is built from wood, very natural.
There's a lot to do. Enjoy the nature in thousand year old tree trunk natural hot tubs, the spa, year-round skiing and snowboarding, whitewater rafting, fishing, horseback riding, hiking, etc. We climbed to the Mocho-Choschuenco volcano which was one of the highlights of the trip. +30 C (86 F), sun shining from clear sky, and you're walking in the snow up, two steps forward, one step backward. After hours of climbing, you're ready to give up and die.
.. and you will feel the pain for the next few days :laugh:
In Queenstown, NZ, we met a chilean from the lake district. As Queenstown is the "adventure capital of the world", he was there to learn and wanted to return to Chile to use his skills. There's a lot of potential in the region.
From Santiago you can also fly to Eastern Island (you know what's there). There's also the Robinson Crusoe Island but the island's only village was hit pretty hard by the tsunami from the recent big earthquake, and now it's more of an destination for rebuilding than tourism. We tried to go there a year ago but couldn't fit it in our schedule.
Driving in Chile was very easy. We never felt unsafe and overall Chile is safer place than rest of South America but the usual warnings apply, especially in the more crowded cities. We even took hitchhikers to our car when we returned from Huilo Huilo -- a child with her mother, they didn't speak english and it was a small, in the middle of nowhere gravel road. English isn't that widely spoken.
I hope to get back to Chile soon. Once, twice, at least a dozen times
Not to the big cities or Santiago as such but there is so much to see and experience in that long stretching country. From the Atamaca desert to the Chilean Patagonia.
PS. To get a better idea, put the place names in Google and hit "Images".